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Progress MS-21 re-supplies the ISS

The third and final Russian cargo mission to the International Space Station, ISS, in 2022 lifted off in the early hours of October 26 and successfully docked at the outpost two days later.

Previous mission: Progress MS-20


Progress MS-21 mission at a glance:

Spacecraft designation(s) Progress MS-21, 11F615 No. 451, ISS mission 82P
Launch vehicle Soyuz-2-1a 14A14-1a No. Ya15000-057
Payload fairing 11S517A2 No. Ya15000-127
Launch site Baikonur, Site 31, Pad 6
Mission Cargo delivery to the ISS
Launch date and time 2022 Oct. 26, 03:20:09.237 Moscow Time
Docking date and time 2022 Oct. 28, 05:48:54 Moscow Time
Docking destination ISS, Russian Segment, Poisk module (MIM2), zenith port
Mission duration 247 days (planned as of early 2022)
Spacecraft mass ~7.4 tons

Preparations for the Progress MS-21 mission

In a preliminary ISS flight manifest drafted in 2014, the third Russian cargo mission to the ISS in 2022 was penciled for October 16, but in early January 2022, Roskosmos announced the plan to launch Progress MS-21 on October 26 of that year. At that time, the 82nd Progress flight to the station was expected to last 247 days.

According to Roskosmos, the spacecraft was expected to carry 2,520 kilograms of cargo to the station, including 702 kilograms of propellant for refueling the station, 420 kilograms of drinking water, 41 kilogram of nitrogen, as well as 1,357 kilograms of supplies in its pressurized compartment for Expedition 68 aboard the ISS. A total of 47.78 kilograms of deliverable materials aimed to support following experiments: Splankh, Neiroimmunitet, Korrektsiya, Impakt and Terminator, Matreshka-R, OMIKi-SPK, Vzaimodeistvie-2, Biodegradatsiya, Separatsiya, Dispersiya. The cargo also included filament rolls for the experimental 3D printer on the station.

Mass breakdown of the cargo delivered aboard Progress MS-20, according to the mission control in Korolev:

Hardware for onboard systems
427 kilograms
Means of medical support
45 kilograms
Personal protection equipment
64 kilograms
Sanitary and hygiene equipment
238 kilograms
Means of servicing and repair
12 kilograms
Means of crew support
38 kilograms
336 kilograms
12 kilograms
Additional hardware
184 kilograms

Preparations for flight

The newly manufactured spacecraft arrived at Baikonur by rail from Korolev on Oct. 25, 2021. The cargo ship underwent vacuum tests between September 12 and 20, after which it was installed at its processing rig inside the spacecraft processing building at Site 254 and where it was connected to diagnostics equipment kicking off its active pre-launch operations. Processing operations included pressurization tests of the propellant lines, loading of thermal-control fluids and filling of the Rodnik water delivery system, final operations with onboard computer and radio systems and the loading of the ship's pressurized compartment with cargo for the ISS.

The 22-car train carrying components of the Soyuz-2-1a rocket for the Progress MS-21 mission arrived at Site 112 in Baikonur from a production factory in Samara in the second half of June 2022 and its unloading proceeded on June 29. The payload fairing for the mission arrived at the site in the second half of August 2022.

The active campaign for the launch started around Sept. 1, 2022, when specialists attached the four strap-on boosters of the first stage to the core stage of the Soyuz-2-1a rocket. In the meantime, the cargo ship was transferred into the anechoic chamber inside processing building at Site 254 for testing of its radio equipment. From September 12 to 19, the ship was undergoing air leak tests in the vacuum chamber at Hall 103.

On Sept. 30, 2022, a routine testing of the ship's solar panels started, involving their exposure to an array of electric lights.

On Oct. 10, 2022, a meeting of technical management in Baikonur cleared the spacecraft for irreversible operations, including loading of propellant into the ship's re-fueling section and into its own integrated propulsion system. Ahead of the trip to the fueling facility at Site 31, the ship underwent weighing and balancing inside the processing building at Site 254. The fueling operations began on October 11 and were completed on October 13. The vehicle was then returned to Site 254 and installed back at its processing rig for closeout operations.

On October 17, Progress MS-21 was integrated with its launch vehicle adapter ring serving as an interface with the Soyuz rocket. The operation was concluded with a test activation of the ship's command and telemetry system and with the preparation for the final visual inspection of the vehicle, which took place on October 19. On the same day, the spacecraft was rolled inside its payload fairing. After a simulation of launch readiness, the payload section was prepared for the transfer to the rocket assembly building at Site 31.


The fully assembled vehicle was rolled out to the launch pad at Site 31 on the morning of Oct. 22, 2022.

According to the Russian mission control, key operations on the launch pad had the following timeline:

  • 48:00:00 - 00:50:00: Thermal conditioning of the spacecraft;
  • 03:30:00 - 03:00:00: Loading of fuel aboar the launch vehicle;
  • 03:00:00 - 00:30:00: Testing of equipment and of onboard systems;
  • 02:50:00 - 00:30:00: Loading of the oxidizer aboard the launch vehicle;
  • 02:45:00 - 01:30:00: Cooling and loading of the liquid nitrogen;
  • 02:20:00 - 01:50:00: Loading of the hydrogen peroxide aboard the rocket;
  • 00:45:00 - 00:30:00: Retraction of the lower access platform and access gantry.

Progress MS-21 enters orbit

A Soyuz rocket carrying the Progress MS-21 cargo ship (ISS mission 82P) lifted off from Site 31 in Baikonur on Oct. 26, 2022, at 03:20:09.237 Moscow Time (8:20 p.m. EDT on October 25).

Following vertical liftoff under the combined thrust of the four RD-107 engines on the first stage and the single RD-108 of the second (core) stage, the launch vehicle headed eastward from Baikonur matching its ground track to an orbit inclined 51.67 degrees to the plane of the Equator.

The four first-stage boosters separated nearly two minutes after liftoff at an altitude of around 43 kilometers at 03:22:07 Moscow Time, followed by the split and drop of the two halves of the payload fairing slightly more than a minute later at an altitude of around 90 kilometers, just above the dense atmosphere and around 200 kilometers downrange at 03:23:12 Moscow Time. In the meantime, the second stage continued firing until 4 minutes and 47 seconds into the flight, bringing the vehicle to around 143 kilometers above the planet and the speed of around four kilometers per second, some 500 kilometers downrange from the launch site at 03:24:56 Moscow Time.

The third stage ignited moments before the separation of the second stage, firing its RD-0110 engine through a lattice structure connecting the two boosters and ensuring a continuous thrust during the separation process. A fraction of a second after the boosters of the second and third stage parted ways, the aft cylindrical section of the third stage split into three segments and dropped off, ensuring the fall of the second stage and the aft section into the same drop zone.

The third stage continued firing and inserted the cargo ship into an initial parking orbit nearly nine minutes after liftoff at 03:28:58 Moscow Time. The mission targeted the 240 by 193-kilometer orbit with an inclination 51.67 degrees to the Equator. Mission control later reported that the spacecraft separation command was issued at 03:28:19 Moscow Time and the parameters of the initial orbit were as following:

  • Orbital period: 88.55 minutes;
  • Inclination: 51.67 degrees toward the Equator;
  • Perigee: 193.05 kilometers;
  • Apogee: 241.24 kilometers.

At the time when Progress MS-19 entered orbit over Siberia, the ISS was ahead over the Pacific, near the cost of Japan, in a 414,299 by 436,696-kilometer orbit.

According to NASA, Progress MS-21 successfully deployed its solar arrays and antennas immediately after the separation from the launch vehicle. The Russian mission control showed the following timeline for initial operations in orbit:

  • 03:32 - 03:36 Moscow Time: Test of the Kurs rendezvous equipment;
  • 04:58 - 05:06 Moscow Time: Extension of the docking mechanism probe into the operational position.

Upon reaching orbit, mission control in Korolev displayed time confirmations for completed milestones:

  • 03:29:00 Moscow Time: Separation of from the third stage of the launch vehicle;
  • 03:29:15 Moscow Time: Deployment of the antennas of the RTS radio system;
  • 03:29:23 Moscow Time: Deployment of solar panels;
  • 03:29:13 Moscow Time: Deployment of the rendezvous antennas.

Progress MS-21 arrives at ISS


Originally, the docking of Progress MS-21 with the ISS was scheduled to take place two days after launch, but in May 2022, Head of Roskosmos Dmitry Rogozin said that a one-orbit (2-hour 46-minute) rendezvous profile could be tested during a cargo mission in the Fall of that year. Based on publications in the official Russian press, the "one-orbit" rendezvous scenario remained on the books as late as September 2022, but it was ultimately replaced with a two-day (34-orbit) flight profile to the station. As usual, it included six major orbit-correction maneuvers using main SKD engine and small DPO thrusters planned during the autonomous rendezvous with the station on Oct. 28, 2022:

Moscow Time
Range to ISS
Velocity change
Burn duration
Engine used
487.72 kilometers
35.78 m/s
90.4 sec.
188.36 kilometers
1.35 m/s
35.0 sec.
80.92 kilometers
39.81 m/s
99.4 sec.
2.20 kilometers
5.82 m/s
17.4 sec.
1.04 kilometers
5.67 m/s
73.8 sec.
0.61 kilometers
1.61 m/s
28.0 sec.

The autonomous rendezvous process between Progress MS-21 and the station was planned according to the following timeline:

Start of the autonomous rendezvous 03:26:23 Moscow Time
Activation of the rendezvous equipment on the Zvezda Service Module 04:15:23 Moscow Time
Activation of the rendezvous equipment on the cargo ship 04:16:23 Moscow Time
Flyaround starts 05:26 Moscow Time
Flyaround completed and station-keeping period 05:40 Moscow Time
Final approach starts 05:40 Moscow Time
Final approach completed 05:51 Moscow Time
Contact 05:51:20 Moscow Time
Docking process begins 05:51 Moscow Time
Docking process ends 06:08 Moscow Time

Progress MS-21 was expected to perform an automated rendezvous and docking with the zenith (sky-facing) port of the Poisk module, MIM2, a part of the Russian ISS Segment on Oct. 28, 2022, at 05:49 Moscow Time (10:49 p.m. EDT on October 27).

In preparation for docking, Russian cosmonauts aboard the ISS conducted a test of the TORU manual rendezvous system, which was expected to be in a standby mode during the final approach of the cargo ship in case of proplems with the automated rendezvous system.

In the meantime, Progress MS-21 fired its DPO thrusters on Oct. 27, 2022, at 04:09:43 Moscow Time, delivering a velocity change of 1,126 meters per second and climbing the 257.17 by 292.75-kilometer orbit, as it continued its chase of the ISS.

After a total of six orbit corrections, the cargo ship was expected to climb to a 377.262 by 426.004-killometer orbit during the 34th revolution of the mission, with an apogee around 10 kilometers below that of the ISS, predicted to be in a 413,974 by 436.974-kilometer orbit at that time.

Following the successful rendezvous, Progress MS-21 performed a flyaround of the station to align itself with the destination docking port and, after a few moments in station keeping, proceeded with an automated final approach around 05:36 Moscow Time on October 28 (10:36 p.m. EDT on October 27). The contact between the cargo ship and the station took place as planned at 05:48:54 Moscow Time on Oct. 28, 2022, (10:48 p.m. EDT on October 27), as the two vehicles were approaching the coast of Chile over the Sothern Pacific. The hard docking was successfully completed around five minutes later, at 05:54 Moscow Time on October 28, (10:54 p.m. EDT on October 27).



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This page is maintained by Anatoly Zak; Last update: November 9, 2022

Page editor: Alain Chabot; Last edit: October 25, 2022

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Progress MS-21 during tests in anechoic chamber in early September 2022. Click to enlarge. Credit: RKK Energia


Progress MS-21 shortly after its integration with the launch vehicle adapter. Click to enlarge. Credit: Roskosmos


Integration of the payload section with the third stage, which was emblazoned with a design dedicated to the Rostov Region. Click to enlarge. Credit: Roskosmos


Soyuz-2-1a rocket with Progress MS-21 is installed on the launch pad. Click to enlarge. Credit: Roskosmos


Opening of a solar panel aboard Progress MS-21 shortly after reaching orbit as seen by an onboard camera. Credit: Roskosmos



Progress MS-21 fires its thrusters during the planned flyaround of the ISS as seen by the station's camera around 05:33 Moscow Time on Oct. 28, 2022. Credit: NASA